Cardiothoracic Surgery Research

Loma Linda University Department of Cardiothoracic Surgery invests in research to challenge and improve current practices and standards. Through research activities and clinical trials, LLUMC physicians contribute to innovations in cardiothoracic surgery while advancing the health and care of patients worldwide.


With extensive training in clinical and research settings, our doctors are committed to contributing to the medical field by publishing their studies and findings in scientific journals and books.

Human neonatal cardiovascular progenitors: unlocking the secret to regenerative ability. Fuentes TI, Appleby N, Tsay E, Martinez JJ, Bailey L, Hasaniya N, Kearns-Jonker M. PLoS One. 2013 Oct 28;8(10):e77464. doi: 10.1371/journal.pone.0077464. eCollection 2013. PMID: 24204836 [PubMed - in process]

Left thoracotomy: an ideal approach for mitral valve replacement in patient with severe chest wall deformity. Bastidas JG, Razzouk AJ, Hasaniya NW, Bailey LL. Ann Thorac Surg. 2013 Sep;96(3):e63-4. doi: 10.1016/j.athoracsur.2013.03.031. PMID: 23992732 [PubMed - indexed for MEDLINE]

Surgery for metastatic neuroendocrine tumors with occult primaries. Bartlett EK, Roses RE, Gupta M, Shah PK, Shah KK, Zaheer S, Wachtel H, Kelz RR, Karakousis GC, Fraker DL. J Surg Res. 2013 Sep;184(1):221-7. doi: 10.1016/j.jss.2013.04.008. Epub 2013 Apr 25. PMID: 23643298 [PubMed - indexed for MEDLINE]

High-dose hypofractionated proton beam radiation therapy is safe and effective for central and peripheral early-stage non-small cell lung cancer: results of a 12-year experience at Loma Linda University Medical Center. Bush DA, Cheek G, Zaheer S, Wallen J, Mirshahidi H, Katerelos A, Grove R, Slater JD. Int J Radiat Oncol Biol Phys. 2013 Aug 1;86(5):964-8. doi: 10.1016/j.ijrobp.2013.05.002. PMID: 23845845 [PubMed - indexed for MEDLINE]

Back to the future! Bold new indication for pulmonary artery banding. Bailey LL. J Heart Lung Transplant. 2013 May;32(5):482-3. doi: 10.1016/j.healun.2013.03.001. No abstract available. PMID: 23570740 [PubMed - indexed for MEDLINE]

Bullet embolization from an aorto-caval fistula to the heart. Pan GZ, Bastidas JG, Hasaniya NW, Floridia R Jr. Interact Cardiovasc Thorac Surg. 2013 May;16(5):710-1. doi: 10.1093/icvts/ivt006. Epub 2013 Jan 25. PMID: 23355649 [PubMed - indexed for MEDLINE]

A rare case of hepatic duct injury from blunt abdominal trauma. Hasaniya NW, Premaratne S, Premaratne ID, McNamara JJ. Am J Case Rep. 2013 Apr 12;14:106-8. doi: 10.12659/AJCR.883881. Print 2013. PMID: 23826446 [PubMed]

Isolation, Characterization, and Spatial Distribution of Cardiac Progenitor Cells in the Sheep Heart. Hou X, Appleby N, Fuentes T, Longo LD, Bailey LL, Hasaniya N, Kearns-Jonker M. J Clin Exp Cardiolog. 2012 Oct 11;S6. pii: 004. PMID: 23539675 [PubMed]

Blake drains: a novel method of chest drainage after extracardiac fontan operation with autologous pericardium. Gordon BM, Hasaniya NW, Newcombe JB, Daher NS, Jodhka U, Razzouk AJ, Bailey LL. Ann Thorac Surg. 2012 Oct;94(4):1289-94. doi: 10.1016/j.athoracsur.2012.03.077. PMID: 23006686 [PubMed - indexed for MEDLINE]

A study of pipeline drugs in neuroendocrine tumors. Anthony CT, Bastidas JG, Thomson JL, Lyons J 3rd, Lewis JM, Schwimer JE, Casey P, Abadie J, Frey DJ, Wang YZ, Boudreaux JP, Woltering EA. J Gastrointest Cancer. 2012 Jun;43(2):296-304. doi: 10.1007/s12029-011-9286-9. PMID: 21556722 [PubMed - indexed for MEDLINE]

Amelioration of ischemia-reperfusion injury in an isolated rabbit lung model using OXANOH. Hasaniya NW, Premaratne S, Zhang WW, Razzuk A, Abdul-Ghani AA, Dashwood RH, Eklof B, Tinsley L, McNamara JJ. Vasc Endovascular Surg. 2011 Oct;45(7):581-91. doi: 10.1177/1538574410390715. PMID: 21984026 [PubMed - indexed for MEDLINE]

Real time three-dimensional transesophageal echocardiographic evaluation of a sinus venosus atrial septal defect. Perez L, Razzouk A, Bansal RC. Echocardiography. 2011 Apr;28(4):E82-4. doi: 10.1111/j.1540-8175.2010.01314.x. Epub 2010 Sep 26. PMID: 20868438 [PubMed - indexed for MEDLINE]

Heart transplantation for congenital heart disease in the first year of life. Chinnock RE, Bailey LL. Curr Cardiol Rev. 2011 May;7(2):72-84. doi: 10.2174/157340311797484231. PMID: 22548030 [PubMed - indexed for MEDLINE]

Aortic root surgery does not increase the operative risk of acute type A aortic dissection. Montalvo J, Razzouk A, Wang N, Bansal R, Rasi A, Hasaniya N, Floridia R, Bailey L.
Am Surg. 2011 Jan;77(1):88-92. PMID: 21396313 [PubMed - indexed for MEDLINE]

Late outcome after repair of mitral valve rupture during balloon atrial septostomy in a neonate. Sachdeva A, Bansal RC, Bailey LL, Razzouk AJ. Tex Heart Inst J. 2011;38(4):412-4. PMID: 21841871 [PubMed - indexed for MEDLINE]

Origins of neonatal heart transplantation: an historical perspective. Bailey LL. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2011;14(1):98-100. doi: 10.1053/j.pcsu.2011.01.004. PMID: 21444055 [PubMed - indexed for MEDLINE]

In situ pericardial extracardiac lateral tunnel Fontan operation: fifteen-year experience. Hasaniya NW, Razzouk AJ, Mulla NF, Larsen RL, Bailey LL. J Thorac Cardiovasc Surg. 2010 Nov;140(5):1076-83. doi: 10.1016/j.jtcvs.2010.07.068. PMID: 20951258 [PubMed - indexed for MEDLINE]

Mortality reduction with beta-blockers in ischemic cardiomyopathy patients undergoing coronary artery bypass grafting. Lin T, Hasaniya NW, Krider S, Razzouk A, Wang N, Chiong JR. Congest Heart Fail. 2010 Jul-Aug;16(4):170-4. doi: 10.1111/j.1751-7133.2010.00146.x. PMID: 20662870 [PubMed - indexed for MEDLINE]

Spigelian hernia as a cause of small bowel obstruction. Bastidas JG, Khan AR, LeBlanc KA. South Med J. 2010 Jun;103(6):567-9. doi: 10.1097/SMJ.0b013e3181de2dc8. PMID: 20710143 [PubMed - indexed for MEDLINE]

Pericardial constriction after cardiac transplantation. Bansal R, Perez L, Razzouk A, Wang N, Bailey L. J Heart Lung Transplant. 2010 Mar;29(3):371-7. doi: 10.1016/j.healun.2009.07.015. Epub 2009 Oct 4. Review. PMID: 19804990 [PubMed - indexed for MEDLINE]

Modification of ventricular-to-pulmonary shunt to minimize proximal conduit obstruction after stage I Norwood reconstruction. Hasaniya NW, Shattuck H, Razzouk A, Bailey L. Ann Thorac Surg. 2010 Jan;89(1):e4-6. doi: 10.1016/j.athoracsur.2009.08.079. PMID: 20103195 [PubMed - indexed for MEDLINE]

The evolution of infant heart transplantation. Bailey LL. J Heart Lung Transplant. 2009 Dec;28(12):1241-5. doi: 10.1016/j.healun.2009.07.021. Epub 2009 Oct 8. No abstract available. PMID: 19818649 [PubMed - indexed for MEDLINE]

A unique complication of a broken heart. Bansal RC, Lin T, Shaker R, Rasi A, Jutzy KR, Razzouk A. Am J Med. 2009 Oct;122(10):910-2. doi: 10.1016/j.amjmed.2009.06.010. No abstract available. PMID: 19786158 [PubMed - indexed for MEDLINE]

Cause of death in pediatric and infant heart transplant recipients: review of a 20-year, single-institution cohort. Zuppan CW, Wells LM, Kerstetter JC, Johnston JK, Bailey LL, Chinnock RE. J Heart Lung Transplant. 2009 Jun;28(6):579-84. doi: 10.1016/j.healun.2009.02.012. Epub 2009 May 5. PMID: 19481018 [PubMed - indexed for MEDLINE]

Pediatric transplantation using hearts refused on the basis of donor quality. Bailey LL, Razzouk AJ, Hasaniya NW, Chinnock RE. Ann Thorac Surg. 2009 Jun;87(6):1902-8; discussion 1908-9. doi: 10.1016/j.athoracsur.2009.03.090. PMID: 19463617 [PubMed - indexed for MEDLINE]

Improving outcomes through the use of surgical sealants for anastomotic sealing during cardiovascular surgery. DeAnda A Jr, Elefteriades JA, Hasaniya NW, Lattouf OM, Lazzara RR. J Card Surg. 2009 May-Jun;24(3):325-33. doi: 10.1111/j.1540-8191.2009.00809.x. Review. PMID: 19438792 [PubMed - indexed for MEDLINE]